755 research outputs found

    La documentación audiovisual en las empresas audiovisuales locales e instituciones universitarias andaluzas

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    Estado actual del proyecto, desarrollado por el Grupo de Investigación en Comunicación Científica y Desarrollo del Departamento de Periodismo de la Universidad de Sevilla, sobre la situación real de la práctica documental en las empresas audiovisuales de la Comunidad Autónoma Andaluza.State of the proyect, developed by the Research Group in Scientific Communication and Development of the Departament of Journalism of the University of Sevilla, on the current real situation of the documentary practice in the audiovisual organizations of Andalucía

    Root temperature and energy consumption at different cable depths in electrically heated substrates

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    A finite element method-based model of a substrate heated by an electric heating cable buried in a thermal isolated container was experimentally validated with root mean square error values of root zone temperature ranging 0.25 to 0.62 ºC. The two-dimensional transient model allowed variations in the physical properties of the substrate with temperature, water content and depth. The operation of nine configurations of a heating cable buried in sand at different depths (50 to 450 mm, at 50 mm intervals) at 200 mm spacing was simulated and assessed. The validated model was used to perform 24-h simulations applying boundary conditions, and substrate moisture content was experimentally obtained at a mean substrate surface temperature of 13.98 ºC. Such simulations reproduced the operation of the heating system by setting a reference temperature of 20 ºC at the control point in the root zone. Burying the heating cable in the surface layers of the substrate caused large temperature gradients and high heat losses through the substrate surface. Accordingly, average temperature in the root zone increased with heating cable depth, up to the 200 mm depth. For greater depths, temperature in the root zone was constant. The ON/OFF control was most effective with the heating cable buried in the root zone and at control point temperatures of 20 ± 1 ºC. Burying the heating cable in the surface layers required higher energy consumption, up to 28 % at 50 mm. The most efficient heating cable depth was 350 mm, with a daily energy consumption of 6750 kJ m-2.S

    El disfraz varonil en el teatro español de los Siglos de Oro

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    La literatura está llena de voces femeninas y masculinas y, por tanto, codificada en múltiples discursos sexualizados. La diferencia sexual, que presenta un componente biológico –previo a toda estructuración lingüística o retórica–, responde a una formación social y cultural; esto es, sufre un proceso de semiotización. La asignación de estereotipos relacionados con el género está presente a lo largo de la historia en todas las culturas, y los Siglos de Oro de la literatura española no son una excepción

    Comparison of coal chars prepared in different devices at similar temperature

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    The characteristics of chars prepared in both a drop tube furnace (DTF) and a flat flame burner (FFB) at 1300 ºC from seven coals of different rank and maceral composition are the subject of this study. Coal samples sized and sieved to 36-75 μm were fed. The flame temperature of the FFB was achieved with a mixture of methane, air and oxygen whereas two different gas compositions were used in the DTF to account for sub-stoichiometric (2.5% O2) and close to stoichiometric (10% O2) oxygen levels. Determination of micropore surface area was carried out by CO2 adsorption isotherms at 0°C and char reactivity to air was measured at 550 °C in a thermogravimetric analyser (TGA). Overall similar combustion trends were obtained in both devices with burnout decreasing as coal rank increases and CO2 surface areas decreasing up to the medium volatile bituminous coal rank and increasing again for the anthracites. The results reveal a reasonable agreement between burnouts of FFB chars and low oxygen DTF chars whereas higher burnouts were obtained for higher oxygen DTF chars. The CO2 surface areas of the chars reasonably scattered without any systematic trend. The intrinsic reactivities of both series of chars from the DTF were similar to the corresponding FFB chars. Increasing coal rank, intrinsic reactivity of chars from the different combustion conditions decreased.The Principality of Asturias (Principado de Asturias), Project PC04-03 and the Ministry for Education (Ministerio de Educación), Project PSE2-2005Peer reviewe

    Social Learning for Facilitating Dialogue and Understanding of the Ecosystem Services Approach: Lessons from a Cross-Border Experience in the Alboran Marine Basin

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    Social learning (SL) appears to have considerable potential to enhance the impact of the ecosystem services approach (ESA) discourse on policy and society. However, empirical research to better understand the processes that support SL, the effects it generates, and the conditions that enable such learning is limited. This study assesses the ability of SL to enhance dialogue and understanding of the ESA to support transformative social change in governance practice in the Alboran Marine Basin. To do so, we conducted a specifically designed SL process oriented towards the ESA as a governance approach in this marine region. The SL process was developed through three interlinked workshops involving scientists, decision-makers and local users from Spain and Morocco, the two countries that share the governance of this social-ecological system. The results revealed that the SL process progressively facilitated (i) a more inclusive and constructive ecosystem services dialogue, (ii) a better understanding of the social-ecological system in which the actors were embedded, (iii) an enhanced recognition of science-policy-society complementarities to address sustainability issues, and (iv) a gradual social transformation towards more sustainable and equitable governance. Via the SL process, a variety of factors were identified as contributing to the creation of four relevant conditions that facilitated its successful operationalisation. These conditions included (i) the generation of trust and shared understanding, (ii) the facilitation of knowledge exchanges between actor groups across frontiers, (iii) the promotion of more democratic participation, and (iv) the co-production of practical outcomes. These contextual insights provided empirical evidence of the prominent role SL can play to enhance dialogue and understanding of the ESA for supporting its adoption as governance practice. On this basis, it is argued that operationalising SL in those processes focused on making the ESA relevant to policy and society is pivotal to its implementation in governance practice

    Dietary Intake and Associated Factors in Long-Term Care Homes in Southeast Spain

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    Diet is a key modifiable factor in the management of malnutrition and age-related diseases such as sarcopenia, an important issue in long-term care homes. The objectives of this study were to evaluate the dietary intake of residents, define dietary patterns, and analyze their association with sex, diet texture, nutritional status, and the presence of sarcopenia. Intake was assessed by the precise weighing method, dietary patterns were defined a posteriori by cluster analysis, and nutritional status and sarcopenia were evaluated by applying the MNA-SF test and EWGSOP algorithm, respectively. A regular diet was consumed by 63% of participants; 56% were at risk of malnutrition and 63% were diagnosed with sarcopenia. Intake of potassium, magnesium, zinc, iodine, vitamin D, E, folic acid, and fiber was low in >80% of participants. Protein intake was <1 g/kg/day in 56% of participants and <25 g/meal in 100%. Two dietary patterns were identified, but neither fully met recommendations. The risk of a poorer diet was higher in females and residents with sarcopenia and was lower in those consuming regular diets. In conclusion, action is required to improve the inadequate nutritional intake of long-term care residents

    Long-term priming of hypothalamic microglia is associated with energy balance disturbances under diet-induced obesity

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    Exposure of microglia to an inflammatory environment may lead to their priming and exacerbated response to future inflammatory stimuli. Here we aimed to explore hypothalamic microglia priming and its consequences on energy balance regulation. A model of intracerebroventricular administration of neuraminidase (NA, which is present in various pathogens such as influenza virus) was used to induce acute neuroinflammation. Evidences of primed microglia were observed 3 months after NA injection, namely (1) a heightened response of microglia located in the hypothalamic arcuate nucleus after an in vivo inflammatory challenge (high fat diet [HFD] feeding for 10 days), and (2) an enhanced response of microglia isolated from NA-treated mice and challenged in vitro to LPS. On the other hand, the consequences of a previous NA-induced neuroinflammation were further evaluated in an alternative inflammatory and hypercaloric scenario, such as the obesity generated by continued HDF feeding. Compared with sham-injected mice, NA-treated mice showed increased food intake and, surprisingly, reduced body weight. Besides, NA-treated mice had enhanced microgliosis (evidenced by increased number and reactive morphology of microglia) and a reduced population of POMC neurons in the basal hypothalamus. Thus, a single acute neuroinflammatory event may elicit a sustained state of priming in microglial cells, and in particular those located in the hypothalamus, with consequences in hypothalamic cytoarchitecture and its regulatory function upon nutritional challenges.Ministerio de Economía, Industria yCompetitividad, Gobierno de España, Grant/Award Number: SAF2017-83645; Ministeriode Educación y Formación Profesional; Funding for open access charge: Universidadde Málaga/CBU

    Application of Proteomic Technologies to Assess the Quality of Raw Pork and Pork Products: An Overview from Farm-To-Fork

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    The quality assurance of pork meat and products includes the study of factors prior to slaughter such as handling practices, diet and castration, and others during the post-mortem period such as aging, storage, and cooking. The development over the last two decades of high-throughput techniques such as proteomics offer great opportunities to examine the molecular mechanisms and study a priori the proteins in the living pigs and main post-mortem changes and post-translational modifications during the conversion of the muscle into the meat. When the most traditional crossbreeding and rearing strategies to improve pork quality were assessed, the main findings indicate that metabolic pathways early post-mortem were affected. Among the factors, it is well documented that pre-slaughter stress provokes substantial changes in the pork proteome that led to defective meat, and consequently, novel protein biomarkers should be identified and validated. Additionally, modifications in pork proteins had a strong effect on the sensory attributes due to the impact of processing, either physical or chemical. Maillard compounds and protein oxidation should be monitored in order to control proteolysis and volatile compounds. Beyond this, the search of bioactive peptides is becoming a paramount goal of the food and nutraceutical industry. In this regard, peptidomics is a major tool to identify and quantify these peptides with beneficial effects for human healthJosé M. Lorenzo and Daniel Franco are members of the HealthyMeat network, funded by CYTED (Programa Iberoamericano de Ciencia y Tecnología para el Desarrollo) (ref. 119RT0568). Our thanks go to GAIN (Axencia Galega de Innovación, Xunta de Galicia, Spain) for supporting this research (grant number IN607A2019/01). Mohammed Gagaoua is grateful to the funding received from Marie Skłodowska-Curie, grant agreement no. 713654S

    Long-Term Measurement of Piglet Activity Using Passive Infrared Detectors

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    Measuring animal activity is useful for monitoring animal welfare in real time. In this regard, passive infrared detectors have been used in recent years to quantify piglet activity because of their robustness and ease of use. This study was conducted on a commercial farm in Northwest Spain during six complete breeding cycles. The hourly average activity of weaned piglets with a body mass of 6–20 kg was recorded and further analyzed by using a multiplicative decomposition of the series followed by a wavelet analysis. Finally, the real series were compared to the theoretical models of activity. Results showed a high level of movement immediately after weaning and a sustained level of activity throughout the cycles. The daily behavior of the piglets followed a clear circadian pattern with several peaks of activity. No differences in behavior were observed between spring–summer cycles and autumn–winter cycles. Single-peak models achieved the best predictive results. In addition, the installed sensors were found to underestimate mild activityThis research was funded by Consellería de Educación, Universidade e Formación Profesional and Consellería de Economía, Emprego e Industria da Xunta de Galicia, grant number ED431B 2018/12-GPCS

    Partial inhibition of CSF1R signaling reverses long-term microglial priming.

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    Microglial cells are main actors in acute neuroinflammation, during which they activate to later return to a basal resting state. Sometimes they retain immune memory of previous neuroinflammatory events, turning into primed microglia, which develop exacerbated responses to new stimuli. Brain can be depleted of microglia by treatment with the CSF1R inhibitor PLX5622. Treatment termination allows for microglia regeneration, new cells presenting a resting state. Here we aimed to explore if treatment with lower doses of PLX5622 can reverse microglial priming. We induced microglial priming in mice by provoking acute neuroinflammation by icv administration of neuraminidase. After 3 weeks, when neuroinflammation is largely solved, mice were treated with a daily dose of PLX5622 for 12 days. Then, microglial repopulation was allowed for 7 weeks. Finally, a second stimulus was applied (ip LPS) to induce inflammatory activation of primed microglia, and animals were sacrificed 12 hours later. Brains were collected to analyze microglial cell number and activation by morphological analysis, and expression level of key genes by qPCR; these parameters were evaluated in two regions: the periventricular area of the hypothalamus and the hippocampus. In hypothalamic paraventricular nucleus the number of microglial cells was the same regardless the treatment; however, it was slightly reduced in the dentate gyrus of the hippocampus of PLX5622 treated mice. Morphological analysis of microglial cells was carried out by fractal, sholl and skeleton analysis. All of them pointed that microglia sampled from NA injected mice had a more activated profile (less ramified cells), which was reversed by PLX5622 treatment. Besides, expression of pro-inflammatory related genes (IL1β, IL6, TNFα, NLRP3, TLR4) pointed to the same direction. Thus, our results suggest that PLX5622 used at low doses reverses microglial priming, while does not fully deplete microglial population.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech
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